Designing better weapons against cancer cells
Jae-Woong Chang, PhD, initially had his eye on medical school. But then his high school teacher pointed out: “Doctors can cure about only...
Engineering better treatments for AML
“This is a very innovative approach. Using precise gene editing, we hypothesize that we can change one protein in healthy hematopoietic stem...
CCRF uses impact investments to accelerate new treatments
For researchers, it’s known as “the valley of death.” It’s the often-unfunded middle territory between the early part of research, when new...
Tackling toxic elements to target terrible diseases
Tiny scraps of paper from newborn screening tests, each with a dried blood spot smaller than a dime, could unlock insights into how to...
Targeting the MN1 protein in hard-to-treat cancers
As a medical student, Kathrin Bernt, MD, initially thought she was going to be a surgeon. “I loved the idea that you have a patient who is re...
Osteosarcoma update: beating an ancient disease at its source
Osteosarcoma, a deadly bone cancer, was first found in a shell-less turtle from the Triassic period. For the last 240 million years, the diseas...
Fewer side-effects and no relapse – A leukemia researcher’s goal
Today, when a child is diagnosed with leukemia, they’re told they are in for a long battle. Those years will include toxic treatments that ca...
Data’s not the flashiest, but it’s the key to childhood cancer
Troves of data around the globe could get us closer to answering the overarching questions: why do kids get cancer, and how can we treat each c...
CCRF announces $10.5 million in new grants
Children’s Cancer Research Fund (CCRF) is proud to award $10.5 million in its latest round of funding. The new grants support 12 research...
Why childhood cancers are considered “too rare” to get research funding
Each day, 43 children are diagnosed with cancer in the United States. That adds up to nearly 16,000 per year. So why is nearly every...
Curiously acting cells inspire new treatments for retinoblastoma
They say the best things that happen are unexpected. In Timothy Hallstrom’s lab, some retinoblastoma cells and immune cells acted so curiousl...
Painting the Picture of Germ Cell Tumors in Kids
Over the last 9 years, Jenny Poynter, PhD, assembled the largest collection of genetic samples of pediatric germ cell tumors available in the...
Our top 5 childhood cancer research wins of 2020
Following the outbreak of COVID-19, Beau Webber, PhD, an expert in genetic engineering and stem cell research, had to essentially shut down...
Researchers use “biological scissors” to cut off paths for osteosarcoma
Osteosarcoma, a deadly bone cancer, has many lethal talents: it can shuffle around its genome to evade therapies, confuse the immune system,...
A Cure in the Making for Osteosarcoma
In talking about a new project to develop new treatments for osteosarcoma, University of Minnesota researcher Beau Webber, PhD, uses a word he ...
The Road to a Clinical Trial for Childhood Brain Tumors
A new brain tumor treatment developed by researchers Christopher Moertel, MD and Michael Olin, PhD received Investigational New Drug (IND)...
Relieving Insomnia in Childhood Cancer Survivors
Eric Zhou, PhD at Dana-Farber Cancer Institute in Boston is studying how to relieve insomnia for childhood cancer survivors. The problem: Child...
An “Achilles Heel” for Mixed-Lineage Leukemia
Maxim Pimkin, MD, PhD at Dana-Farber Cancer Institute in Boston is exploring how depleting two proteins in the body could save children with an...