CCRF-funded researcher uses microscopic protein pathways to beat graft-versus-host disease
Kids like Alex often need blood or marrow transplants (BMTs) as part of their treatment plans. Typically, these transplants use immune cells...
Researchers investigate existing drugs to treat AML more safely
The last time Children’s Cancer Research Fund donors heard about Ani Deshpande, Ph.D. assistant professor at Sanford Burnham Prebys Medical...
Crossing international borders in retinoblastoma research
For kids, rare means fewer doctors understand how to treat their disease, it’s difficult to find and develop better treatments, and hard to...
Minnesota couple’s $925,000 gift funds leading edge cancer technology at the University of Minnesota
Above: Fritz and Glenda Corrigan, pictured with their children and grandchildren. In April 2021, staff at the University of Minnesota finished ...
Designing better weapons against cancer cells
Jae-Woong Chang, PhD, initially had his eye on medical school. But then his high school teacher pointed out: “Doctors can cure about only...
Engineering better treatments for AML
“This is a very innovative approach. Using precise gene editing, we hypothesize that we can change one protein in healthy hematopoietic stem...
CCRF uses impact investments to accelerate new treatments
For researchers, it’s known as “the valley of death.” It’s the often-unfunded middle territory between the early part of research, when new...
Tackling toxic elements to target terrible diseases
Tiny scraps of paper from newborn screening tests, each with a dried blood spot smaller than a dime, could unlock insights into how to...
Targeting the MN1 protein in hard-to-treat cancers
As a medical student, Kathrin Bernt, MD, initially thought she was going to be a surgeon. “I loved the idea that you have a patient who is re...
Osteosarcoma update: beating an ancient disease at its source
Osteosarcoma, a deadly bone cancer, was first found in a shell-less turtle from the Triassic period. For the last 240 million years, the diseas...
Fewer side-effects and no relapse – A leukemia researcher’s goal
Today, when a child is diagnosed with leukemia, they’re told they are in for a long battle. Those years will include toxic treatments that ca...
Data’s not the flashiest, but it’s the key to childhood cancer
Troves of data around the globe could get us closer to answering the overarching questions: why do kids get cancer, and how can we treat each c...
CCRF announces $10.5 million in new grants
Children’s Cancer Research Fund (CCRF) is proud to award $10.5 million in its latest round of funding. The new grants support 12 research...
Why childhood cancers are considered “too rare” to get research funding
Each day, 43 children are diagnosed with cancer in the United States. That adds up to nearly 16,000 per year. So why is nearly every...
Curiously acting cells inspire new treatments for retinoblastoma
They say the best things that happen are unexpected. In Timothy Hallstrom’s lab, some retinoblastoma cells and immune cells acted so curiousl...
Painting the Picture of Germ Cell Tumors in Kids
Over the last 9 years, Jenny Poynter, PhD, assembled the largest collection of genetic samples of pediatric germ cell tumors available in the...
Our top 5 childhood cancer research wins of 2020
Following the outbreak of COVID-19, Beau Webber, PhD, an expert in genetic engineering and stem cell research, had to essentially shut down...
Researchers use “biological scissors” to cut off paths for osteosarcoma
Osteosarcoma, a deadly bone cancer, has many lethal talents: it can shuffle around its genome to evade therapies, confuse the immune system,...