This September, your generosity, advocacy and awareness-building made a mighty big difference. This Childhood Cancer Awareness Month, CCRF awarded nine new research projects at different institutions across the country. This brings CCRF’s total to over $94 million in research grants nationwide.

These 9 new research projects aim to:

• Investigate how a newly discovered regulatory pathway drives neuroblastoma development and creating targeted therapies to defeat the disease.
• Perfect a more precise “pulse” technology to eliminate the guesswork involved in determining solid tumor margins during surgery.
• Develop better understanding of pediatric thyroid cancer with the goal of developing individualized treatments specifically for kids.
• Discover a drug that will help two proteins prevent a newly developed Ewing sarcoma therapy from being too toxic.
• Create a behavioral insomnia intervention program for kids with cancer who have trouble sleeping because of pain or anxiety caused by cancer treatment.
• Use data to better understand how cells in a tumor and a child’s immune cells interact.
• Improve current CAR T cell treatments for acute lymphoblastic leukemia using ultrasound, allowing treatment to begin immediately.
• Study proteins that regulate the work of genes and how depleting these proteins could be the ‘Achilles heel’ for certain leukemia cells.
• Target previously ‘undruggable’ proteins in acute lymphoblastic leukemia.

Cancer is a mighty big problem to solve, but we’ve got incredibly bright, dedicated people on our side in this fight. But without you, many of these research projects may never have received the funding they needed to move forward. Your generosity gives these researchers the resources they need to explore new ideas and uncover safer, more effective treatments and cures for childhood cancer.