Discovering the cell origin of Ewing sarcoma
For decades, the question of Ewing sarcoma’s genetic beginnings has stumped scientists, leaving potential therapeutic targets...
Exploring unconventional paths to new treatments for childhood rhabdoid tumors
Capucine Van Rechem was still a teenager when cancer stole away both her parents. First her mother died of breast cancer, and then her father p...
CCRF-funded researcher to open immunotherapy clinical trial for hepatoblastoma
O’Neill, a recipient of the Emerging Scientist Award from Children’s Cancer Research Fund (CCRF), is studying a new therapy to treat children...
8 new scientists will kickstart their projects thanks to CCRF
Many great ideas go unexplored in the childhood cancer world due to a lack of funding. Thanks to donors like you, eight new projects are...
Setting the Stage for First-Ever Targeted Treatment of an Extremely Rare Sarcoma
Dr. Okimoto studies a deadly subset of sarcoma, cancer that develops in the bone or tissue, called CIC-DUX4 sarcoma. He estimates only about...
Sneaking past medulloblastoma’s micro-defenses
CCRF Emerging Scientist Award winner Giedre Krenciute is developing a Trojan horse of sorts to sneak past medulloblastoma’s armed defenses...
CCRF-funded researcher uses microscopic protein pathways to beat graft-versus-host disease
Kids like Alex often need blood or marrow transplants (BMTs) as part of their treatment plans. Typically, these transplants use immune cells...
Researchers investigate existing drugs to treat AML more safely
The last time Children’s Cancer Research Fund donors heard about Ani Deshpande, Ph.D. assistant professor at Sanford Burnham Prebys Medical...
Crossing international borders in retinoblastoma research
For kids, rare means fewer doctors understand how to treat their disease, it’s difficult to find and develop better treatments, and hard to...
Minnesota couple’s $925,000 gift funds leading edge cancer technology at the University of Minnesota
Above: Fritz and Glenda Corrigan, pictured with their children and grandchildren. In April 2021, staff at the University of Minnesota finished ...
Designing better weapons against cancer cells
Jae-Woong Chang, PhD, initially had his eye on medical school. But then his high school teacher pointed out: “Doctors can cure about only...
Engineering better treatments for AML
“This is a very innovative approach. Using precise gene editing, we hypothesize that we can change one protein in healthy hematopoietic stem...
CCRF uses impact investments to accelerate new treatments
For researchers, it’s known as “the valley of death.” It’s the often-unfunded middle territory between the early part of research, when new...
Tackling toxic elements to target terrible diseases
Tiny scraps of paper from newborn screening tests, each with a dried blood spot smaller than a dime, could unlock insights into how to...
Targeting the MN1 protein in hard-to-treat cancers
As a medical student, Kathrin Bernt, MD, initially thought she was going to be a surgeon. “I loved the idea that you have a patient who is re...
Osteosarcoma update: beating an ancient disease at its source
Osteosarcoma, a deadly bone cancer, was first found in a shell-less turtle from the Triassic period. For the last 240 million years, the diseas...
Fewer side-effects and no relapse – A leukemia researcher’s goal
Today, when a child is diagnosed with leukemia, they’re told they are in for a long battle. Those years will include toxic treatments that ca...
Data’s not the flashiest, but it’s the key to childhood cancer
Troves of data around the globe could get us closer to answering the overarching questions: why do kids get cancer, and how can we treat each c...