Leukemia Archives - Children's Cancer Research Fund https://childrenscancer.org/tag/leukemia/ Children's Cancer Research Fund invests in lifesaving, leading-edge research in the prevention, diagnosis, treatment, and cure of childhood cancers and blood-related disorders. Mon, 29 Apr 2024 21:15:07 +0000 en-US hourly 1 The power of seed funding: CCRF-funded leukemia screening project lands NIH grant https://childrenscancer.org/the-power-of-seed-funding-ccrf-funded-leukemia-screening-project-lands-nih-grant/ Fri, 27 Oct 2023 15:26:24 +0000 https://childrenscancer.org/?p=13794 Erin Marcotte, PhD, MPH, and Heather Nelson, PhD, MPH, of University of Minnesota are seizing the opportunity to turn small things into big hope for the future of childhood leukemia. In 2016, the pair received a grant from Children’s Cancer Research Fund (CCRF) to develop a new method to predict which children are at risk of developing acute lymphoblastic leukemia (ALL) — and perhaps one day prevent it.

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]]> Bone marrow recipient Ella is flower girl in her donor’s wedding https://childrenscancer.org/bone-marrow-recipient-ella-is-flower-girl-in-her-donors-wedding/ Tue, 17 Oct 2023 20:30:32 +0000 https://childrenscancer.org/?p=13734 Ella had a very aggressive form of acute myeloid leukemia, and neither of her siblings were a marrow match. Even after the transplant, she had only a 10% chance of making it past the one-year mark. But thanks to Cody’s whim decision in college to donate marrow, Ella was able to participate in his wedding as one of their flower girls three years after her transplant.

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]]> Developing a new way to stop the most aggressive leukemia https://childrenscancer.org/developing-a-new-way-to-stop-the-most-aggressive-leukemia/ Thu, 24 Aug 2023 17:51:16 +0000 https://childrenscancer.org/?p=13307 With support from an Accelerating Impact for Hard-to-Treat Cancer Award from Children’s Cancer Research Fund (CCRF), University of Virginia researcher John Bushweller is pursuing an innovative new way to treat this devastating disease. Bushweller has found that blocking the MLL protein from binding to DNA stops leukemia cell growth completely — like corking a bottle so that nothing can spill out. Now he and his team at UVA Cancer Center are developing drugs to disrupt the DNA binding process.

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]]> Engineering better treatments for AML https://childrenscancer.org/engineering-better-treatments-for-aml/ Mon, 23 Aug 2021 14:47:40 +0000 https://childrenscancer.org/?p=9247 “This is a very innovative approach. Using precise gene editing, we hypothesize that we can change one protein in healthy hematopoietic stem cells and make it invisible to the antibody while preserving its physiologic function,” Genovese explained. “This would allow the administration of highly effective immunotherapies targeting a protein essential for cancer survival without the risk of severe toxicity on the healthy tissue.”

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]]> Treating Leukemia with Microbubbles https://childrenscancer.org/treating-leukemia-with-microbubbles/ Mon, 16 Mar 2020 16:27:30 +0000 https://childrenscancer.org/?p=5956 Texas Caroline de Gracia Lux , PhD at the University of Texas, Southwestern in Texas will use novel ultrasound technology to make acute lymphoblastic leukemia CAR-T cell treatment less toxic and improve the quality of life during treatment.  The problem: Currently, CAR T-cell immunotherapy is the best way to cure relapsed acute lymphoblastic leukemia, one of the most common cancers in children. Unfortunately, this type of ...

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]]> CCRF Funds 9 New Research Projects https://childrenscancer.org/ccrf-funds-9-new-research-projects/ Thu, 19 Sep 2019 17:05:57 +0000 https://childrenscancer.org/?p=4912 This September, your generosity, advocacy and awareness-building made a mighty big difference. This Childhood Cancer Awareness Month, CCRF awarded nine new research projects at different institutions across the country. This brings CCRF’s total to over $94 million in research grants nationwide. These 9 new research projects aim to: Investigate how a newly discovered regulatory pathway drives neuroblastoma development and creating targeted therapies to defeat the ...

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]]> Targeting Chemoresistant Leukemia Cells https://childrenscancer.org/targeting-chemoresistant-leukemia-cells/ Mon, 03 Jun 2019 21:18:46 +0000 https://childrenscancer.org/?p=4463 Sometimes, leukemia cancer cells are so powerful they can overcome the most potent of chemotherapies. Because of support in part by Children's Cancer Research Fund's donors, Peter Gordon, MD, PhD, an oncologist and researcher at the University of Minnesota, and his team could explore the reasons this happens, opening potential new avenues for treatment options for acute lymphoblastic leukemia (ALL) and more. According to Dr. ...

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]]> Cancer Survival and Socioeconomic Status https://childrenscancer.org/cancer-survival-and-socioeconomic-status/ Tue, 05 Mar 2019 20:19:51 +0000 https://childrenscancer.org/?p=4161 Racial and ethnic disparities have long plagued health care, but according to Children's Cancer Research Fund Chief Medical Advisor Logan Spector, PhD, no one knew quite how much or how exactly these disparities affected African-American and Hispanic children with cancer. So Dr. Spector's team delved into this question: Why do African-American and Hispanic children die of cancer more often? Is the disparity caused by socioeconomic ...

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]]> Being a Grandparent https://childrenscancer.org/being-a-grandparent/ Wed, 26 Apr 2017 20:04:33 +0000 https://childrenscancer.org/?p=1399 The post Being a Grandparent appeared first on Children's Cancer Research Fund.

]]> Carpe Diem https://childrenscancer.org/carpe-diem/ Thu, 20 Apr 2017 17:37:35 +0000 https://childrenscancer.org/?p=1373 The post Carpe Diem appeared first on Children's Cancer Research Fund.

]]> Meet the Researchers: Megan Voss, DNP, RN https://childrenscancer.org/meet-the-researchers-megan-voss-dnp-rn/ Wed, 05 Apr 2017 19:03:30 +0000 http://dev.childrenscancer.org/?p=1262 The post Meet the Researchers: Megan Voss, DNP, RN appeared first on Children's Cancer Research Fund.

]]> Building Up Leukemia Patients’ Immune Systems https://childrenscancer.org/building-up-leukemia-patients-immune-systems/ Thu, 29 Dec 2016 15:54:03 +0000 http://dev.childrenscancer.org/?p=467 The post Building Up Leukemia Patients’ Immune Systems appeared first on Children's Cancer Research Fund.

]]> 2016 Research Highlights: What Donors Made Possible https://childrenscancer.org/2016-research-highlights-what-donors-made-possible/ Thu, 10 Nov 2016 16:03:51 +0000 http://dev.childrenscancer.org/?p=420 The post 2016 Research Highlights: What Donors Made Possible appeared first on Children's Cancer Research Fund.

]]> 2015 Research Highlights: What Donors Made Possible https://childrenscancer.org/2015-research-highlights-what-donors-made-possible/ Sat, 05 Dec 2015 18:20:57 +0000 http://dev.childrenscancer.org/?p=1256 The post 2015 Research Highlights: What Donors Made Possible appeared first on Children's Cancer Research Fund.

]]> Cancer Requires us to Create a “New Normal” https://childrenscancer.org/cancer-requires-us-to-create-a-new-normal/ Sat, 07 Nov 2015 20:56:42 +0000 http://dev.childrenscancer.org/?p=196 The post Cancer Requires us to Create a “New Normal” appeared first on Children's Cancer Research Fund.

]]> Mikaela’s Story: Surviving Acute Myeloid Leukemia https://childrenscancer.org/mikaelas-story-surviving-acute-myeloid-leukemia/ Mon, 24 Nov 2014 15:58:23 +0000 http://dev.childrenscancer.org/?p=978 The post Mikaela’s Story: Surviving Acute Myeloid Leukemia appeared first on Children's Cancer Research Fund.

]]> Kendal’s Story https://childrenscancer.org/kendals-story/ Sat, 31 Mar 2012 15:30:03 +0000 http://dev.childrenscancer.org/?p=1235 The post Kendal’s Story appeared first on Children's Cancer Research Fund.

]]> Alijah’s Story: Surviving Acute Lymphocytic Leukemia (ALL) https://childrenscancer.org/alijahs-story-surviving-acute-lymphocytic-leukemia-all/ Fri, 24 Feb 2012 20:06:02 +0000 http://dev.childrenscancer.org/?p=1034 The post Alijah’s Story: Surviving Acute Lymphocytic Leukemia (ALL) appeared first on Children's Cancer Research Fund.

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